Within the last decade, the CeMM became an institution of essential importance at the heart of the Austrian R&D community, attracting more than 150 leading scientists from over 40 nations. CeMM contributes substantially to the fight against inflammatory diseases, immune disorders, cancer and rare diseases. After 10 years of excellent work at CeMM, the election of Prof. Dr. Giulio Superti-Furga as a Member of the European Research Council in the beginning of the year reflects the institution’s outstanding achievements. The ERC membership offers considerable opportunities, as the council represents the most important funding institution for excellent fundamental research across the EU – a responsible and challenging duty especially in times of political instability. Indeed, R&D financing is vital for the life‑science sector both at EU and national level which has a huge economic impact: in Austria it comprises over 800 companies, with more than 52.000 employees and an overall annual turnover of 19.1 Billion Euro. Besides funding, the main success factors for a strong life-science sector are a highly educated workforce, state of the art infrastructure and technology transfer. In this light, CeMM is a crucial institution at the interface of fundamental research and practice orientation in a clinical environment. I hope that CeMM will continue its great success story: Happy 10th Birthday to CeMM and its scientists!