The adult lung consists of different, highly specialized cell types that are protected by a variety of immune cells. Using advanced single cell sequencing methods, researchers of the Weizmann Institute of Science in Israel, the CeMM and the Medical University in Vienna discovered a hitherto unknown, fundamental role of basophils in the development of macrophages in the lung. The study, published in Cell, could open new clinical strategies to fight lung diseases.

Lungs are vital organs required for the uptake of oxygen in exchange for carbon dioxide. However, the enormous complexity of the respiratory organ is often underestimated and…

We are happy and proud to announce a new piece of art located in the small seminar room at CeMM:

Stiegenhaus, 11 Square Albin Cachot, 75013 Paris-13E / RC01-BDJ 2018
Balsa wood, lacquer, multi-part
approx. 270 x 520 x 32 cm

The artwork is a generous gift from our befriended artist Klaus Pamminger who has already contributed a piece of art to the CeMM Brain Lounge. Until Summer 2018 the wall sculpture was part of the exhibition COLLAGE at the Fotogalerie Wien. The sculpture “Stiegenhaus” shows construction lines that Klaus Pamminger took from the film Belle de Jour (1967) derived from the staircase that Séverine Sérizy (Catherine Deneuve)…

Glioblastoma is a brain cancer with devastating prognosis. A new collaborative study by scientists from CeMM, MedUni Vienna and the Austrian Brain Tumor Registry network demonstrates how epigenetic analysis of tumor samples collected in routine clinical practice could be used to better classify and treat the disease. The results were published in Nature Medicine.

Glioblastoma is an aggressive brain cancer with a high degree of molecular heterogeneity among the cancer cells. This results in evolutionary selection for those cells that can withstand drug treatment. In order to develop better therapies for glioblastoma, detailed knowledge…

The rearrangement of the cell´s inner scaffold, the cytoskeleton, is a vital process for immune cells. In a new collaborative study, led by scientists from LBI-RUD/CeMM, a rare inherited disease revealed a hitherto unknown role of a cytoskeleton-regulating factor for the proper functioning of the adaptive immune system. The study was published in the Journal of Allergy and Clinical Immunology.

In order to move, a body needs a strong scaffold. This is not only true on a macroscopic level, where animals rely on skeletons to support their muscles. It is also true on a cellular level: the cytoskeleton composed of actin filaments is crucial for…

Patients with congenital diarrheal disorders, a group of rare inherited diseases with largely unknown mechanisms, suffer from severe to life-threatening diarrhea and nutrient malabsorption from birth. Using state-of-the-art genetic and molecular biology analysis methods involving the revolutionary gut organoid technology, researchers from the LBI-RUD and CeMM, together with the Medical University of Innsbruck and University Medical Center Utrecht identified the largest cohort of DGAT1-deficient patients to date. The scientists also unveiled the molecular mechanisms of the affected protein and discovered its crucial role in fat digestion. 

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EU-LIFE, the alliance of 13 leading life science research institutes in Europe announced its reaction to the European Commission´s proposal for Horizon Europe, the next Framework Programme for Research and Innovation (FP9) that will run from 2021 to 2027. 

The key points are as follows: 

• EU-LIFE urges the European Parliament and the EU Council to push for a stronger Horizon Europe by raising its budget as recommended by several reports

• EU-LIFE encourages Horizon Europe to expand the extremely successful programmes it has initiated, namely the ERC grant system and Marie Skłodowska-Curie Actions, in addition to collaborative projects…