Groups
Cell division-dependent dissemination following E-cadherin loss underlies initiation of diffuse-type gastric cancer
Jooske L Monster, Lars Js Kemp, Georg A Busslinger, Marjolein J Vliem, Lucca Lm Derks, Annelot Al Staes, Tanya M Bisseling, Hans Clevers, Rachel S van der Post, Martijn Gloerich.J Pathol 2024 Jun;263(2):226-241. doi: 10.1002/path.6277.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38572612/
Inhibition of ATGL alleviates MASH via impaired PPARα signalling that favours hydrophilic bile acid composition in mice
Emmanuel Dauda Dixon, Thierry Claudel, Alexander Daniel Nardo, Alessandra Riva, Claudia Daniela Fuchs, Veronika Mlitz, Georg Busslinger, Hubert Scharnagl, Tatjana Stojakovic, Joana Senéca, Helga Hinteregger, Gernot F Grabner, Dagmar Kratky, Henkjan Verkade, Robert Zimmermann, Guenter Haemmerle, Michael Trauner.J Hepatol 2024 Sep 30:S0168-8278(24)02577-7. doi: 10.1016/j.jhep.2024.09.037.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39357546/
Tuft cells act as regenerative stem cells in the human intestine
Lulu Huang, Jochen H Bernink, Amir Giladi, Daniel Krueger, Gijs F van Son, Maarten H Geurts, Georg Busslinger, Lin Lin, Harry Begthel, Maurice Zandvliet, Christianne J Buskens, Willem A Bemelman, Carmen Lopez-Iglesias, Peter J Peters, Hans Clevers.Nature 2024 Oct;634(8035):929-935. doi: 10.1038/s41586-024-07952-6.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39358509/
Description and functional validation of human enteroendocrine cell sensors
Joep Beumer, Maarten H Geurts, Veerle Geurts, Amanda Andersson-Rolf, Ninouk Akkerman, Franziska Völlmy, Daniel Krueger, Georg A Busslinger, Adriana Martinez-Silgado, Charelle Boot, Fjodor A Yousef Yengej, Jens Puschhof, Wiline J Van de Weterin, Kevin Knoops, Carmen Lopez-Inglesis, Peter J Peters, Judith A Vivie, Dylan Mooijman, Johan H van Es, Hans Clevers.Science 2024 Oct;18;386(6719):341-348. doi: 10.1126/science.adl1460.
Abstract: https://pubmed.ncbi.nlm.nih.gov/39418382/
Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet
Mathilde Meyenberg, Anna Hakobyan, Nikolina Papac-Milicevic, Laura Göderle, Franziska L Langner, Mateo Markovic, Ji-Hyun Lee, Bon-Kyoung Koo, Georg A Busslinger, Israel Tojal da Silva, Christoph J Binder, Jörg Menche, Joanna I Loizou.Sci Rep. 2023 Aug 26;13(1):13964. doi: 10.1038/s41598-023-41123-3.
Abstract: https://pubmed.ncbi.nlm.nih.gov/37633982/
GLP-2 improves hepatic inflammation and fibrosis in Mdr2-/-mice via activation of NR4a1/Nur77 in hepatic stellate cells and intestinal FXR signaling
Claudia D Fuchs, Thierry Claudel, Veronika Mlitz, Alessandra Riva, Moritz Menz, Ksenia Brusilovskaya, Felix Haller, Maximilian Baumgartner, Philipp Königshofer, Lukas W Unger, Wilhelm Sjöland, Hubert Scharnagl, Tatjana Stovakovic, Georg Busslinger, Thomas Reiberger, Hanns-Ulrich Marschall, Michael Trauner.Cell Mol Gastroenterol Hepatol 2023;16(5):847-856. doi: 10.1016/j.jcmgh.2023.08.003.
Abstract: https://pubmed.ncbi.nlm.nih.gov/37572734/
Transcription shapes 3D chromatin organization by interacting with loop extrusion
Edward J Banigan, Wen Tang, Aafke A van den Berg, Roman R Stocsits, Gordana Wutz, Hugo B Brandão, Georg A Busslinger, Jan-Michael Peters, Leonid A Mirny.Proc Natl Acad Sci U S A 2023 Mar 14;120(11):e2210480120. doi: 10.1073/pnas.2210480120.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36897969/
Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes
Georg A Busslinger.Mol Cell Oncol. 2022 Jan 22;9(1):2026559. doi: 10.1080/23723556.2022.2026559. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35252552/