CeMM Adjunct Principal Investigator
Translational Immunology of the Skin & Mucous Membranes
Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases
Medical University of Vienna
Department of Dermatology
The research projects of Georg Stary are focusing on different aspects of host-pathogen interactions and the contribution of tissue-resident leukocytes to physiologic and pathologic immune responses. Georg’s research interest lies in the biology, longevity, turnover and function of tissue-resident leukocytes in peripheral tissue with the skin being an optimal and accessible organ to perform meaningful human experiments. Georg Stary is a member of the Immuno-Board for Rare and Undiagnosed Diseases organized by LBI-RUD and CeRUD Director Kaan Boztug, and the Stary laboratory is applying omics technologies in collaboration with research groups at CeMM and LBI-RUD.
Georg Stary is a fully trained dermatovenereologist with direct contact to patients and ample experience in research in organ-specific immunological processes. After a 4-year fellowship in the von Andrian Laboratory at Harvard Medical School, he became Senior Physician and Principal Investigator to the Department of Dermatology of the Medical University of Vienna in 2014. He was appointed Assistant Professor in 2015 and Associate Professor in 2016. Since November 2018, he has been an Adjunct Principal Investigator at LBI-RUD and CeMM and has since been named Co-Director of LBI-RUD. His research projects focus on different aspects of host-pathogen interactions and the contribution of tissue-resident leukocytes to physiological and pathological immune responses. His research projects are in the areas of biology, immune cell longevity, turn-over and function of tissue-resident leukocytes in peripheral tissue. The skin often serves as model tissue being accessible for translational experimental setups. He is a member of the Immuno-Board for Rare and Undiagnosed Diseases organized by LBI-RUD and CeRUD and in many national and international clinical and scientific societies.
Stary G, Olive A, Radovic-Moreno AF, Gondek D, Alvarez D, Basto PA, Perro M, Vrbanac VD, Tager AW, Shi J, Yethon LA, Langer R, Farokhzad OC, Starnbach M, von Andrian UH: A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells. Science, 348(6241):aaa8205. doi: 10.1126/science.aaa8205, 2015. (abstract)
Brüggen MC, Petzelbauer P, Greinix H, Contassot E, Jankovic D, French L, Socié G, Rabitsch W, Kuzmina Z, Kalhs P, Knobler R, Stingl G, Stary G: Epidermal elafin expression is an indicator of poor prognosis in cutaneous graft-versus-host disease. J Invest Dermatol, 135:999-1006. doi: 10.1038/jid.2014.489, 2015. (abstract)
Brüggen MC, Klein I, Greinix H, Bauer W, Kuzmina Z, Rabitsch W, Kalhs P, Petzelbauer P, Knobler R, Stingl G, Stary G: Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease. Blood, 123:290-299. doi: 10.1182/blood-2013-07- 514372, 2014. (abstract)
Stary G, Klein I, Kohlhofer S, Koszik F, Scherzer T, Müllauer L, Quendler H, Kohrgruber N, Stingl G: Plasmacytoid dendritic cells express TRAIL and induce CD4+ T cell apoptosis in HIV-1 viremic patients. Blood, 114:3854-3863. doi: 10.1182/blood-2009-04-217927, 2009. (abstract)
Stary G, Bangert C, Tauber M, Strohal R, Kopp T, Stingl G: Tumoricidal activity of TLR7/8- activated inflammatory dendritic cells. J Exp Med; 204:1441-1451, 2007. (abstract)